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Co-occurrence of mcr-1 and blaKPC-2 in a clinical isolate of Escherichia coli in Brazil

4 May 2017

Abstract excerpt

Sir, Polymyxins are the last resort for the treatment of infections caused by carbapenem-resistant Enterobacteriaceae (CRE). In November 2015, Liu et al.1 described for the first time a colistin resistance mechanism mediated by a new gene (mcr-1), which was present in a transferable plasmid. Since then, several reports have indicated that mcr-1 has silently spread worldwide since 1980.2 Of particular concern is...

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PMID: 28505353
DOI: 10.1093/jac/dkx142

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