Article
No association detected between seven common variants in the CDKAL1 gene and gestational glycemic traits.
Molecular and cellular probes - 1 Aug 2017
Ju Hongfang, Lin Rong, Yuan Ziyu, Sun Yuantian, Zeng Liangliang, Su Zhenyu, Jin Li
Abstract excerpt
Elevated plasma glucose levels in pregnancy increase adverse pregnancy outcomes. Cyclin-dependent kinase 5 regulatory subunit-associated protein 1-like 1 (CDKAL1) has been shown to be involved in insulin secretion in pancreatic β cells. In this study, we investigated the impact of genetic variants in CDKAL1 on plasma glucose, insulin values, β cell function and insulin resistance in the fasted state as well as...
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