Article
Molecular Markers for Colorectal Cancer.
The Surgical clinics of North America - 1 Jun 2017
Wright Moriah, Beaty Jenifer S, Ternent Charles A
Abstract excerpt
Colorectal cancers develop through at least 3 major pathways, including chromosomal instability, mismatch repair, and methylator phenotype. These pathways can coexist in a single individual and occur in both sporadic and inherited colorectal cancers. In spite of the unique molecular and genetic signatures of colorectal cancers, nonspecific chemotherapy based on the antineoplastic effects of 5-fluorouracil is the...
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