Article
Activation-Induced Autophagy Is Preserved in CD4+ T-Cells in Familial Longevity.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Sept 2017
Raz Yotam, Guerrero-Ros Ignacio, Maier Andrea, Slagboom P Eline, Atzmon Gil, Barzilai Nir, Macian Fernando
Abstract excerpt
As with many other tissues and organs, the immune system is also affected by age. Immunosenescence is characterized by a decreased ability of immune cells to mount a productive response upon exposure to new antigens. Several studies have reported that members of families with exceptional longevity show improved immune function, which might contribute to the increased life- and health-span observed in those...
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