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Does agricultural use of azole fungicides contribute to resistance in the human pathogen Aspergillus fumigatus ?

9 May 2017

Abstract excerpt

Azole resistance in human fungal pathogens has increased over the past twenty years, especially in immunocompromised patients. Similarities between medical and agricultural azoles, and extensive azole (14α-demethylase inhibitor, DMI) use in crop protection, prompted speculation that resistance in patients with aspergillosis originated in the environment. Aspergillus species, and especially Aspergillus fumigatus,...

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PMID: 28485100
DOI: 10.1002/ps.4607

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