Article
EGFR gene mutation in gastrointestinal stromal tumours.
Histopathology - 1 Oct 2017
Shi Shan-Shan, Wu Nan, He Yan, Wei Xue, Xia Qiu-Yuan, Wang Xuan, Ye Sheng-Bin, Li Rui, Rao Qiu, Zhou Xiao-Jun
Abstract excerpt
AIMS: The aim of this study was to evaluate the mutation status of epidermal growth factor receptor (EGFR) in gastrointestinal stromal tumours (GISTs) and its association with various clinicopathological variables, as well as to discuss further the effects of EGFR mutations on tumour formation and progression. METHODS AND RESULTS: A well-characterized cohort of 323 GISTs, obtained between 2010 and 2015 from the...
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