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Article

Molecular Imaging of PARP

4 May 2017

Abstract excerpt

The poly(adenosine diphosphate-ribose)polymerase (PARP) family of enzymes is an important factor in the cellular DNA damage response and has gained much attention for its role in many diseases, particularly cancer. Targeted molecular imaging of PARP using fluorescent or radiolabeled tags has followed on the success of therapeutic inhibitors and gained momentum over the past few years. This review covers PARP...

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PMID: 28473593
DOI: 10.2967/jnumed.117.189936

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