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Article

Apoptosis in Acanthamoeba castellanii belonging to the T4 genotype.

Journal of basic microbiology - 1 Jul 2017

Baig Abdul M, Lalani Salima, Khan Naveed A

Abstract excerpt

Here we describe features of apoptosis in unicellular Acanthamoeba castellanii belonging to the T4 genotype. When exposed to apoptosis-inducing compounds such as doxorubicin, A. castellanii trophozoites exhibited cell shrinkage and membrane blebbing as observed microscopically, DNA fragmentation using agarose gel electrophoresis, and phosphatidylserine (PS) externalization using annexin V immunostaining. Overall,...

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PMID: 28466971
DOI: 10.1002/jobm.201700025

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