Article
Revisiting the Hunter Gaston discriminatory index: Note of caution and courses of change.
Tuberculosis (Edinburgh, Scotland) - 1 May 2017
Mokrousov Igor
Abstract excerpt
Hunter Gaston Discriminatory Index (HGDI) is a widely used estimator of discriminatory power of genotyping methods and diversity of molecular markers in bacterial pathogens, including Mycobacterium tuberculosis. In my opinion, the index is somewhat misleading: a closer look at common practice and particular studies reveals that values in the range of 0.6-0.9 are modest but uncritically perceived as high. I...
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