Article
Aneurysms in neurofibromatosis type 2: Evidence for vasculopathy?
American journal of medical genetics. Part A - 1 Jun 2017
Afridi Shazia K, Thomson Suki, Connor Steve E J, Walsh Daniel C, Ferner Rosalie E
Abstract excerpt
There have been anecdotal reports of vasculopathy associated with Neurofibromatosis Type 2 (NF2). Given the increasing use of bevacizumab, a vascular endothelial growth factor inhibitor which results in an increased risk of bleeding, it is important to ascertain if there is a predisposition to vascular abnormalities in NF2. In our unit NF2 patients undergo annual MRI brain and internal auditory meatus imaging. We...
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