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Retinal and Circulating miRNAs in Age-Related Macular Degeneration: An In vivo Animal and Human Study

29 Mar 2017

Abstract excerpt

Age related macular degeneration (AMD) is the leading cause of blindness among people aged 50 and over. Retinal deposition of amyloid-β (Aβ) aggregates in AMD patients has suggested a potential link between AMD and Alzheimer's disease (AD). We have evaluated the differential retinal expression profile of miRNAs in a rat model of AMD elicited by Aβ. A serum profile of miRNAs in AMD patients has been also assessed...

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PMID: 28424619
DOI: 10.3389/fphar.2017.00168

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