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Article

Association of genetic variations in the mitochondrial DNA control region with presbycusis.

Clinical interventions in aging - 1 Jan 2017

Falah Masoumeh, Farhadi Mohammad, Kamrava Seyed Kamran, Mahmoudian Saeid, Daneshi Ahmad, Balali Maryam, Asghari Alimohamad, Houshmand Massoud

Abstract excerpt

BACKGROUND: The prominent role of mitochondria in the generation of reactive oxygen species, cell death, and energy production contributes to the importance of this organelle in the intracellular mechanism underlying the progression of the common sensory disorder of the elderly, presbycusis. Reduced mitochondrial DNA (mtDNA) gene expression and coding region variation have frequently been reported as being...

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Identifiers

PMID: 28424544
DOI: 10.2147/CIA.S123278
PMCID: PMC5344408

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Source receipt: pubmed, retrieved 7 Sept 2026.

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