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Article

Inheritance patterns of ATCCT repeat interruptions in spinocerebellar ataxia type 10 (SCA10) expansions.

PloS one - 1 Jan 2017

Landrian Ivette, McFarland Karen N, Liu Jilin, Mulligan Connie J, Rasmussen Astrid, Ashizawa Tetsuo

Abstract excerpt

Spinocerebellar ataxia type 10 (SCA10), an autosomal dominant cerebellar ataxia disorder, is caused by a non-coding ATTCT microsatellite repeat expansion in the ataxin 10 gene. In a subset of SCA10 families, the 5'-end of the repeat expansion contains a complex sequence of penta- and heptanucleotide interruption motifs which is followed by a pure tract of tandem ATCCT repeats of unknown length at its 3'-end....

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Identifiers

PMID: 28423040
DOI: 10.1371/journal.pone.0175958
PMCID: PMC5397023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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