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Article

MICA diversity and linkage disequilibrium with HLA-B alleles in renal-transplant candidates in southern Brazil.

PloS one - 1 Jan 2017

Yamakawa Roger Haruki, Saito Patrícia Keiko, Gelmini Geórgia Fernanda, da Silva José Samuel, Bicalho Maria da Graça, Borelli Sueli Donizete

Abstract excerpt

The major histocompatibility complex (MHC) class I chain-related gene A (MICA) is located centromerically to the human leukocyte antigen (HLA)-B. The short distance between these loci in the MHC indicates the presence of linkage disequilibrium (LD). Similarly to the HLA, the MICA is highly polymorphic, and this polymorphism has not been well documented in different populations. In this study, we estimated the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28419176
DOI: 10.1371/journal.pone.0176072
PMCID: PMC5395226

Genes

MICA

Provenance

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