Article
Cassava haplotype map highlights fixation of deleterious mutations during clonal propagation.
Nature genetics - 1 Jun 2017
Ramu Punna, Esuma Williams, Kawuki Robert, Rabbi Ismail Y, Egesi Chiedozie, Bredeson Jessen V, Bart Rebecca S, Verma Janu, Buckler Edward S, Lu Fei
Abstract excerpt
Cassava (Manihot esculenta Crantz) is an important staple food crop in Africa and South America; however, ubiquitous deleterious mutations may severely decrease its fitness. To evaluate these deleterious mutations, we constructed a cassava haplotype map through deep sequencing 241 diverse accessions and identified >28 million segregating variants. We found that (i) although domestication has modified starch and...
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