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Article

Sleep restores place learning to the adenylyl cyclase mutant rutabaga.

Journal of neurogenetics - 1 Mar 2020

Dissel Stephane, Morgan Ellen, Duong Vincent, Chan Dorothy, van Swinderen Bruno, Shaw Paul, Zars Troy

Abstract excerpt

Sleep plays an important role in regulating plasticity. In Drosophila, the relationship between sleep and learning and memory has primarily focused on mushroom body dependent operant-learning assays such as aversive phototaxic suppression and courtship conditioning. In this study, sleep was increased in the classic mutant rutabaga (rut2080) and dunce (dnc1) by feeding them the GABA-A agonist gaboxadol (Gab)....

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Identifiers

PMID: 31997683
DOI: 10.1080/01677063.2020.1720674
PMCID: PMC7250152

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