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Article

EBV MicroRNA BART16 Suppresses Type I IFN Signaling

18 Apr 2017

Abstract excerpt

Type I IFNs play critical roles in orchestrating the antiviral defense by inducing direct antiviral activities and shaping the adaptive immune response. Viruses have evolved numerous strategies to specifically interfere with IFN production or its downstream mediators, thereby allowing successful infection of the host to occur. The prototypic human gammaherpesvirus EBV, which is associated with infectious...

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PMID: 28416598
DOI: 10.4049/jimmunol.1501605

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