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Article

miRNA signatures can predict acute liver failure in hepatitis E infected pregnant females

1 Apr 2017

Abstract excerpt

BACKGROUND: Acute viral hepatitis E (AVH-E) can often result in acute liver failure (ALF) during pregnancy. microRNAs serve as mediators in drug induced liver failure. We investigated their role as a biomarker in predicting ALF due to HEV (ALF-E). METHODS: We performed next generation sequencing and subsequent validation studies in PBMCs of pregnant (P) self limiting AVH-E, ALF due to HEV (ALF-E) and compared...

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Share to Hepatitis Viruses Studies and Epidemiology
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PMID: 28413835
DOI: 10.1016/j.heliyon.2017.e00287

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