Article
Use of Bone Morphogenetic Protein 15 Polymorphisms to Predict Ovarian Stimulation Outcomes in Infertile Brazilian Women.
Genetic testing and molecular biomarkers - 1 May 2017
Peluso Carla, Goldman Cecilia, Cavalcanti Viviane, Gastaldo Guilherme, Trevisan Camila Martins, Christofolini Denise Maria, Barbosa Caio Parente, Bianco Bianca
Abstract excerpt
AIMS: Polymorphisms in the gene encoding bone morphogenetic protein 15 (BMP15) can result in inhibited secretion or lowered bioactivity of the BMP15 protein. BMP15 levels are associated with follicle-stimulating hormone receptor (FSHR) action on granulosa cells, wherein FSHR increases the sensitivity of ovarian follicles to follicle-stimulating hormone (FSH). In this study we evaluated the BMP15 polymorphisms...
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