Article
Lack of association of C3 gene with uveitis: additional insights into the genetic profile of uveitis regarding complement pathway genes.
Scientific reports - 13 Apr 2017
Yang Ming Ming, Wang Jun, Dong Li, Kong De Ju, Teng Yan, Liu Ping, Fan Jiao Jie, Yu Xu Hui
Abstract excerpt
Uveitis is a devastating ocular disease that causes blindness. Our previous studies have achieved great advancements in depicting the genetic profiles of uveitis regarding complement pathway genes. This study aimed to provide additional insights into this interest by testing the "central" factor of the complement system, C3 gene variants, in two uveitis entities. Eight haplotype-tagging SNPs of C3 gene were...
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