Article
Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles.
Cell host & microbe - 12 Apr 2017
Lolle Signe, Greeff Christiaan, Petersen Klaus, Roux Milena, Jensen Michael Krogh, Bressendorff Simon, Rodriguez Eleazar, Sømark Kenneth, Mundy John, Petersen Morten
Abstract excerpt
To establish infection, pathogens deploy effectors to modify or remove host proteins. Plant immune receptors with nucleotide-binding, leucine-rich repeat domains (NLRs) detect these modifications and trigger immunity. Plant NLRs thus guard host "guardees." A corollary is that autoimmunity may result from inappropriate NLR activation because mutations in plant guardees could trigger corresponding NLR guards. To...
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