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Article

Deregulation of the endometrial stromal cell secretome precedes embryo implantation failure

3 Apr 2017

Abstract excerpt

STUDY QUESTION: Is implantation failure following ART associated with a perturbed decidual response in endometrial stromal cells (EnSCs)? SUMMARY ANSWER: Dynamic changes in the secretome of decidualizing EnSCs underpin the transition of a hostile to a supportive endometrial microenvironment for embryo implantation; perturbation in this transitional pathway prior to ART is associated with implantation failure....

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Share to Endometriosis Research and Treatment
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PMID: 28402555
DOI: 10.1093/molehr/gax023

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