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Article

Potentially functional variants in lncRNAs are associated with breast cancer risk in a Chinese population.

Molecular carcinogenesis - 1 Sept 2017

Jiang Yue, Du Fangzhi, Chen Fei, Qin Na, Jiang Zhu, Zhou Jin, Jiang Tao, Pu Zhening, Cheng Yue, Chen Jiaping, Dai Juncheng, Ma Hongxia, Jin Guangfu, Hu Zhibin, Yu Hao, Shen Hongbing

Abstract excerpt

Long non-coding RNAs (lncRNAs) participate in the development of breast cancer. Genetic variants in lncRNAs may be involved in their abnormal expressions and associated with cancer risk. In the present study, we performed RNA sequencing on five paired breast cancer tumor and adjacent non-cancerous tissues to obtain differentially expressed lncRNAs. We systematically selected potential regulatory variants of these...

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PMID: 28398609
DOI: 10.1002/mc.22659

Genes

ERBB2

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