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Identification of Fungal Species in Brain Tissue from Alzheimer’s Disease by Next-Generation Sequencing

7 Apr 2017

Abstract excerpt

The possibility that patients diagnosed with Alzheimer's disease (AD) have disseminated fungal infection has been recently advanced by the demonstration of fungal proteins and DNA in nervous tissue from AD patients. In the present study, next-generation sequencing (NGS) was used to identify fungal species present in the central nervous system (CNS) of AD patients. Initially, DNA was extracted from frozen tissue...

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PMID: 28387676
DOI: 10.3233/jad-170058

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