Article
HoxA10 and HoxA11 Regulate the Expression of Contraction-Associated Proteins and Contribute to Regionalized Myometrium Phenotypes in Women.
Reproductive sciences (Thousand Oaks, Calif.) - 1 Jan 2018
Li Yinan, Li Haolong, Xie Ning, Chen Ruiqi, Lee Ahn Rhi, Slater Donna, Lye Stephen, Dong Xuesen
Abstract excerpt
A relaxed fundus (FUN) and a contracted lower uterine segment (LUS) of human myometrium are required for maintaining pregnancy. How this regional myometrium function is regulated remains unclear. We have previously reported that the homeobox protein A13 (HoxA13) is highly expressed in the LUS and can enhance the expression of contraction-associated proteins (CAPs). Here, we show that in contrast to HoxA13, HoxA10...
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