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Article

Central Role for Dermal Fibroblasts in Skin Model Protection against Candida albicans

24 Mar 2017

Abstract excerpt

The fungal pathogen Candida albicans colonizes basically all human epithelial surfaces, including the skin. Under certain conditions, such as immunosuppression, invasion of the epithelia occurs. Not much is known about defense mechanisms against C. albicans in subepithelial layers such as the dermis. Using immune cell-supplemented 3D skin models we defined a new role for fibroblasts in the dermis and identified a...

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Share to Antifungal resistance and susceptibility
Share to Dermatology and Skin Diseases
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PMID: 28368492
DOI: 10.1093/infdis/jix153

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