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Article

Variants in the host genome may inhibit tumour growth in devil facial tumours: evidence from genome-wide association.

Scientific reports - 24 Mar 2017

Wright Belinda, Willet Cali E, Hamede Rodrigo, Jones Menna, Belov Katherine, Wade Claire M

Abstract excerpt

Devil facial tumour disease (DFTD) has decimated wild populations of Tasmanian devils (Sarcophilus harrisii) due to its ability to avoid immune detection and pass from host to host by biting. A small number of devils have been observed to spontaneously recover from the disease which is otherwise fatal. We have sequenced the genomes of these rare cases and compared them to the genomes of devils who succumbed to...

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PMID: 28341828
DOI: 10.1038/s41598-017-00439-7
PMCID: PMC5428454

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PAX3

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