Article
Heat-Induced Editing of HPV Genes to Clear Mucocutaneous Warts?
The Journal of investigative dermatology - 1 Apr 2017
Piguet Vincent
Abstract excerpt
Hyperthermia increases expression of the antiviral cellular factors APOBEC3A and APOBEC3G and induces G-to-A or C-to-T mutations in human papilloma virus cervical cell lines and genital warts. This unexpected effect of heat treatment correlated with regression of genital warts in a subset of patients, including at distant sites, suggesting that this effect may be mediated in part by antiviral as well as...
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