Article
Genomic landscape of extended-spectrum β-lactamase resistance in Escherichia coli from an urban African setting.
The Journal of antimicrobial chemotherapy - 1 Jun 2017
Musicha Patrick, Feasey Nicholas A, Cain Amy K, Kallonen Teemu, Chaguza Chrispin, Peno Chikondi, Khonga Margaret, Thompson Sarah, Gray Katherine J, Mather Alison E, Heyderman Robert S, Everett Dean B, Thomson Nicholas R, Msefula Chisomo L
Abstract excerpt
Objectives: Efforts to treat Escherichia coli infections are increasingly being compromised by the rapid, global spread of antimicrobial resistance (AMR). Whilst AMR in E. coli has been extensively investigated in resource-rich settings, in sub-Saharan Africa molecular patterns of AMR are not well described. In this study, we have begun to explore the population structure and molecular determinants of AMR amongst...
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