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Piperacillin-Tazobactam versus Other Antibacterial Agents for Treatment of Bloodstream Infections Due to AmpC β-Lactamase-Producing Enterobacteriaceae.

Antimicrobial agents and chemotherapy - 1 Jun 2017

Cheng Lucy, Nelson Brian C, Mehta Monica, Seval Nikhil, Park Sarah, Giddins Marla J, Shi Qiuhu, Whittier Susan, Gomez-Simmonds Angela, Uhlemann Anne-Catrin

Abstract excerpt

In vivo induction of AmpC beta-lactamases produces high-level resistance to many beta-lactam antibiotics in Enterobacteriaceae, often resulting in the need to use carbapenems or cefepime (FEP). The clinical effectiveness of piperacillin-tazobactam (TZP), a weak inducer of AmpC beta-lactamases, is poorly understood. Here, we conducted a case-control study of adult inpatients with bloodstream infections (BSIs) due...

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Identifiers

PMID: 28320724
DOI: 10.1128/AAC.00276-17
PMCID: PMC5444164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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