Article
Generation of Small Colony Variants in Biofilms by Escherichia coli Harboring a Conjugative F Plasmid.
Microbes and environments - 31 Mar 2017
Tashiro Yosuke, Eida Hiroaki, Ishii Satoshi, Futamata Hiroyuki, Okabe Satoshi
Abstract excerpt
A conjugative F plasmid induces mature biofilm formation by Escherichia coli by promoting F-pili-mediated cell-cell interactions and increasing the expression of biofilm-related genes. We herein demonstrated another function for the F plasmid in E. coli biofilms; it contributes to the emergence of genetic and phenotypic variations by spontaneous mutations. Small colony variants (SCVs) were more frequently...
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