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Article

TP53 alterations in primary and secondary Sézary syndrome: A diagnostic tool for the assessment of malignancy in patients with erythroderma.

PloS one - 1 Jan 2017

Gros Audrey, Laharanne Elodie, Vergier Marie, Prochazkova-Carlotti Martina, Pham-Ledard Anne, Bandres Thomas, Poglio Sandrine, Berhouet Sabine, Vergier Béatrice, Vial Jean-Philippe, Chevret Edith, Beylot-Barry Marie, Merlio Jean-Philippe

Abstract excerpt

Recent massive parallel sequencing data have evidenced the genetic diversity and complexity of Sézary syndrome mutational landscape with TP53 alterations being the most prevalent genetic abnormality. We analyzed a cohort of 35 patients with SS and a control group of 8 patients with chronic inflammatory dermatoses. TP53 status was analyzed at different clinical stages especially in 9 patients with a past-history...

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Identifiers

PMID: 28301507
DOI: 10.1371/journal.pone.0173171
PMCID: PMC5354275

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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