The Effect of PCDH15 Gene Variations on the Risk of Noise-induced Hearing Loss in a Chinese Population.

doi:10.3967/bes2017.019

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The Effect of PCDH15 Gene Variations on the Risk of Noise-induced Hearing Loss in a Chinese Population.

Biomedical and environmental sciences : BES - 1 Feb 2017

Xu Xiang Rong, Wang Jing Jing, Yang Qiu Yue, Jiao Jie, He Li Hua, Yu Shan Fa, Gu Gui Zhen, Chen Guo Shun, Zhou Wen Hui, Wu Hui, Li Yan Hong, Zhang Huan Ling, Zhang Zeng Rui, Jin Xian Ning

Abstract excerpt

Noise-induced hearing loss (NIHL) is a complex disease caused by interactions between environmental and genetic factors. This study investigated whether genetic variability in protocadherin related 15 (PCDH15) underlies an increased susceptibility to the development of NIHL in a Chinese population. The results showed that compared with the TT genotype of rs11004085, CT/CC genotypes were associated with an...

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PMID: 28292353
DOI: 10.3967/bes2017.019

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PCDH15

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