Article
A deletion in the Hermansky-Pudlak syndrome 4 (Hps4) gene appears to be responsible for albinism in channel catfish.
Molecular genetics and genomics : MGG - 1 Jun 2017
Li Yueru, Geng Xin, Bao Lisui, Elaswad Ahmed, Huggins Kevin W, Dunham Rex, Liu Zhanjiang
Abstract excerpt
Albinism is caused by a series of genetic abnormalities leading to reduction of melanin production. Albinism is quite frequent in catfish, but the causative gene and the molecular basis were unknown. In this study, we conducted a genome-wide association study (GWAS) using the 250 K SNP array. The GWAS analysis allowed mapping of the albino phenotype in the Hermansky-Pudlak syndrome 4 (Hps4) gene, which is known...
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