Article
Antioxidant Capacity and Superoxide Dismutase Activity in Adrenoleukodystrophy.
JAMA neurology - 1 May 2017
Turk Bela R, Theisen Benjamin E, Nemeth Christina L, Marx Joel S, Shi Xiaohai, Rosen Melissa, Jones Richard O, Moser Ann B, Watkins Paul A, Raymond Gerald V, Tiffany Carol, Fatemi Ali
Abstract excerpt
Importance: X-linked adrenoleukodystrophy (ALD) may switch phenotype to the fatal cerebral form (ie, cerebral ALD [cALD]), the cause of which is unknown. Determining differences in antioxidant capacity and superoxide dismutase (SOD) levels between phenotypes may allow for the generation of a clinical biomarker for predicting the onset of cALD, as well as initiating a more timely lifesaving therapy. Objective: To...
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