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Article

Pituitary Carcinoma in a Patient with an SDHB Mutation.

Endocrine pathology - 1 Dec 2017

Tufton Nicola, Roncaroli Federico, Hadjidemetriou Irene, Dang Mary N, Dénes Judit, Guasti Leonardo, Thom Maria, Powell Michael, Baldeweg Stephanie E, Fersht Naomi, Korbonits Márta

Abstract excerpt

We present the first case of pituitary carcinoma occurring in a patient with a succinate dehydrogenase subunit B (SDHB) mutation and history of paraganglioma. She was initially treated for a glomus tumour with external beam radiotherapy. Twenty-five years later, she was diagnosed with a non-functioning pituitary adenoma, having developed bitemporal hemianopia. Recurrence of the pituitary lesion (Ki-67 10% and p53...

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Share to Adenoma
Share to SDHB gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Neoplasm Recurrence, Local

Share to Neoplasms, Multiple Primary

Share to Pituitary Neoplasms

Share to Succinate Dehydrogenase

Source

Open in PubMed Open full text

Identifiers

PMID: 28284009
DOI: 10.1007/s12022-017-9474-7
PMCID: PMC5694522

Genes

SDHB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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