Article
Glioma Subclassifications and Their Clinical Significance.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics - 1 Apr 2017
Chen Ricky, Smith-Cohn Matthew, Cohen Adam L, Colman Howard
Abstract excerpt
The impact of targeted therapies in glioma has been modest. All the therapies that have demonstrated a significant survival benefit for gliomas in Phase III trials, including radiation, chemotherapy (temozolomide and PCV [procarbazine, lomustine, vincristine]), and tumor-treating fields, are based on nonspecific targeting of proliferating cells. Recent advances in the molecular understanding of gliomas suggest...
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