Article
mir-126 rs4636297 and TGFβRI rs334348 functional gene variants are associated with susceptibility to endometriosis and its severity.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Jun 2017
Sepahi Neda, Kohan Leila, Jahromi Athar Rasekh, Daneshbod Yahya, Hoveidi Elahe Nimi
Abstract excerpt
microRNAs (miRNAs) are negative regulators in a variety of cellular processes that occur in endometriosis. Therefore, functional polymorphisms in miRNA and miRNA binding sites may affect gene expression and contribute to susceptibility of endometriosis. In this study, we evaluated the association of two miRNA related polymorphisms, mir-126 rs4636297 and TGFβRI rs334348, with endometriosis risk and its severity....
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