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Staurosporine Induces Filamentation in the Human Fungal Pathogen Candida albicans via Signaling through Cyr1 and Protein Kinase A

2 Mar 2017

Abstract excerpt

The impact of fungal pathogens on human health is devastating. One of the most pervasive fungal pathogens is Candida albicans , which kills ~40% of people suffering from bloodstream infections. Treatment of these infections is extremely difficult, as fungi are closely related to humans, and there are limited drugs that kill the fungus without host toxicity. The capacity of C. albicans to transition between yeast...

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PMID: 28261668
DOI: 10.1128/msphere.00056-17

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