Article
Primary Ovarian Insufficiency: Current Concepts.
Southern medical journal - 1 Mar 2017
Collins Gretchen, Patel Bansari, Thakore Suruchi, Liu James
Abstract excerpt
A potential consequence of chemotherapy is the destruction of oocytes, resulting in primary ovarian insufficiency (POI) in young patients; this often results in secondary amenorrhea and necessitates hormone replacement therapy. Regardless of the etiology of POI, the chance of pregnancy is low in this patient population. Given the extent to which oocyte depletion or dysfunction is variable, there is the...
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