Article
The control of cardiac ventricular excitability by autonomic pathways.
Pharmacology & therapeutics - 1 Jun 2017
Finlay Malcolm, Harmer Stephen C, Tinker Andrew
Abstract excerpt
Central to the genesis of ventricular cardiac arrhythmia are variations in determinants of excitability. These involve individual ionic channels and transporters in cardiac myocytes but also tissue factors such as variable conduction of the excitation wave, fibrosis and source-sink mismatch. It is also known that in certain diseases and particularly the channelopathies critical events occur with specific...
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