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Article

Variations in gut microbiota and fecal metabolic phenotype associated with depression by 16S rRNA gene sequencing and LC/MS-based metabolomics.

Journal of pharmaceutical and biomedical analysis - 10 May 2017

Yu Meng, Jia Hongmei, Zhou Chao, Yang Yong, Zhao Yang, Yang Maohua, Zou Zhongmei

Abstract excerpt

As a prevalent, life-threatening and highly recurrent psychiatric illness, depression is characterized by a wide range of pathological changes; however, its etiology remains incompletely understood. Accumulating evidence supports that gut microbiota affects not only gastrointestinal physiology but also central nervous system (CNS) function and behavior through the microbiota-gut-brain axis. To assess the impact...

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PMID: 28219800
DOI: 10.1016/j.jpba.2017.02.008

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