Article
Genetic contributions to self-reported tiredness.
Molecular psychiatry - 1 Mar 2018
Deary V, Hagenaars S P, Harris S E, Hill W D, Davies G, Liewald D C M, McIntosh A M, Gale C R, Deary I J
Abstract excerpt
Self-reported tiredness and low energy, often called fatigue, are associated with poorer physical and mental health. Twin studies have indicated that this has a heritability between 6 and 50%. In the UK Biobank sample (N=108 976), we carried out a genome-wide association study (GWAS) of responses to the question, 'Over the last two weeks, how often have you felt tired or had little energy?' Univariate GCTA-GREML...
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