Article
Real-World Experiences With a Direct-Acting Antiviral Agent for Patients With Hepatitis C Virus Infection.
The Permanente journal - 1 Jan 2017
Louie Vincent, Latt Nyan L, Gharibian Derenik, Sahota Amandeep, Yanny Beshoy T, Mittal Rasham, Bider-Canfield Zoe, Cheetham T Craig
Abstract excerpt
CONTEXT: Traditional hepatitis C virus treatment was limited by low cure rates, side effects, and stringent monitoring requirements. Sofosbuvir, a direct-acting antiviral agent with a cure rate of 96%, was introduced in 2013. However, trials frequently excluded patients with advanced liver disease and prior treatment experience. This study aims to elucidate the real-world cure rates and sofosbuvir safety profile....
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