Article
Lactic Acidosis with Chloramphenicol Treatment in a Child with Cystic Fibrosis.
Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique - 30 Jan 2017
Goyer Isabelle, Iseppon Massimiliano, Thibault Céline, Abaji Rachid, Krajinovic Maja, Autmizguine Julie
Abstract excerpt
Children with cystic fibrosis are commonly colonized with multi-resistant bacteria. In such patients, infectious exacerbation may require salvage therapy with uncommonly used antimicrobials, including chloramphenicol. Chloramphenicol is rarely used nowadays because of the associated severe adverse events. We describe the case of a 15-year-old female with terminal cystic fibrosis who required intravenous (IV)...
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