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Article

Prenatal Exposure to Respiratory Syncytial Virus Alters Postnatal Immunity and Airway Smooth Muscle Contractility during Early-Life Reinfections.

PloS one - 1 Jan 2017

Brown Paul M, Harford Terri J, Agrawal Vandana, Yen-Lieberman Belinda, Rezaee Fariba, Piedimonte Giovanni

Abstract excerpt

Maternal viral infections can have pathological effects on the developing fetus which last long after birth. Recently, maternal-fetal transmission of respiratory syncytial virus (RSV) was shown to cause postnatal airway hyperreactivity (AHR) during primary early-life reinfection; however, the influence of prenatal exposure to RSV on offspring airway immunity and smooth muscle contractility during recurrent...

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Source

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Identifiers

PMID: 28178290
DOI: 10.1371/journal.pone.0168786
PMCID: PMC5298216

Genes

AHR
NGF
TNF

Provenance

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