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Development of a human cardiac organoid injury model reveals innate regenerative potential

1 Jan 2017

Abstract excerpt

The adult human heart possesses a limited regenerative potential following an ischemic event, and undergoes a number of pathological changes in response to injury. Although cardiac regeneration has been documented in zebrafish and neonatal mouse hearts, it is currently unknown whether the immature human heart is capable of undergoing complete regeneration. Combined progress in pluripotent stem cell...

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PMID: 28174241
DOI: 10.1242/dev.143966

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