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Article

Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5.

BMC molecular biology - 31 Jan 2017

Zhang Ling, Liu Yunhao, Li Wei, Zhang Qiaoling, Li Yanwei, Liu Junpin, Min Jie, Shuang Chaofan, Song Shizheng, Zhang Zhibing

Abstract excerpt

BACKGROUND: The mammalian sperm-associated antigen 16 gene (Spag16) uses alternative promoters to produce two major transcript isoforms (Spag16L and Spag16S) and encode proteins that are involved in the cilia/flagella formation and motility. In silico analysis of both mouse and human SPAG16L promoters reveals the existence of multiple putative SOX5 binding sites. Given that the SOX5 gene encodes a 48-kDa...

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Source

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Identifiers

PMID: 28137312
DOI: 10.1186/s12867-017-0082-3
PMCID: PMC5282894

Genes

SOX5
SPAG6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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