Article
The anti-tumor activities of Neferine on cell invasion and oxaliplatin sensitivity regulated by EMT via Snail signaling in hepatocellular carcinoma.
Scientific reports - 30 Jan 2017
Deng Ganlu, Zeng Shan, Ma Junli, Zhang Yan, Qu Yanling, Han Ying, Yin Ling, Cai Changjing, Guo Cao, Shen Hong
Abstract excerpt
Tumor invasion and chemotherapy resistance, which are associated with epithelial-mesenchymal transition (EMT), remain as major challenges in hepatocellular carcinoma (HCC) treatment. Neferine, a natural component of Nelumbo nucifera, have been proven the antitumor efficiency in cancer, but the effects of Neferine on HCC invasion and chemosensitivity need to be elucidated. Applying multiple assays of cell...
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