Article
Sofosbuvir in Combination with Simeprevir +/- Ribavirin in Genotype 4 Hepatitis C Patients with Advanced Fibrosis or Cirrhosis: A Real-World Experience from Belgium.
PloS one - 1 Jan 2017
Degré Delphine, Sersté Thomas, Lasser Luc, Delwaide Jean, Starkel Peter, Laleman Wim, Langlet Philippe, Reynaert Hendrik, Bourgeois Stefan, Vanwolleghem Thomas, Negrin Dastis Sergio, Gustot Thierry, Geerts Anja, Van Steenkiste Christophe, de Galocsy Chantal, Lepida Antonia, Orlent Hans, Moreno Christophe
Abstract excerpt
INTRODUCTION: Hepatitis C virus (HCV) is a major global health issue and successful treatment has been associated with a reduction of risk of all-cause mortality. Advancements have been made in HCV treatment through the use of interferon-free regimens. Most trials have been conducted in HCV genotype (GT) 1 and data for interferon-free regimens in GT4 patients are limited. The aim of this study was to evaluate the...
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